Risk of eczema, wheezing and respiratory tract infections in the first year of life: A systematic review of vitamin D concentrations during pregnancy and at birth.

Risk of eczema, wheezing and respiratory tract infections in the first year of life: A systematic review of vitamin D concentrations during pregnancy and at birth.

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BackgroundAllergic conditions and respiratory tract infections (RTIs) are common causes of morbidity and mortality in childhood.The relationship between vitamin D status in pregnancy (mothers), early life (infants) and health outcomes such as allergies and RTIs in infancy is unclear.To date, studies have shown conflicting Cardiovascular Fitness Profile of Sleman Regency PLAPD Volleyball Athletes results.

ObjectiveThis systematic review aims to gather and appraise existing evidence on the associations between serum vitamin D concentrations during pregnancy and at birth and the development of eczema, wheezing, and RTIs in infants.Data sourcesPubMed, MEDLINE, ProQuest, Scopus, CINAHL, Cochrane Library and Academic Search Premier databases were searched systematically using specified search terms and keywords.Study selectionArticles on the associations between serum vitamin D concentrations during pregnancy and at birth and eczema, wheezing, and RTIs among infants (1-year-old and younger) published up to 31 March 2019 were identified, screened and retrieved.

ResultsFrom the initial 2678 articles screened, ten met the inclusion criteria and were included in the final analysis.There were mixed and conflicting results with regards to the relationship THE ROLE OF LEADERSHIP AGILITY AND ORGANIZATIONAL COMMITMENT TOWARD ORGANIZATIONAL READINESS FOR CHANGES IN PUBLIC ISLAMIC UNIVERSITIES OF CENTRAL JAVA IN CONDITIONS OF VUCA ERA between maternal and cord blood vitamin D concentrations and the three health outcomes-eczema, wheezing and RTIs-in infants.ConclusionCurrent findings revealed no robust and consistent associations between vitamin D status in early life and the risk of developing eczema, wheezing and RTIs in infants.

PROSPERO registration no.CRD42018093039.